What is TB-500?

TB-500 is the research-trade designation for synthetic material related to thymosin β4, an actin-sequestering peptide studied in cell motility and repair models.

Research use only. Not for human or veterinary use.

TB-500

Reference profile — not currently in the Vybe catalog

Overview

Thymosin β4 is a 43-residue peptide expressed in many vertebrate tissues and is a major G-actin binding protein. Catalog material sold as TB-500 is a synthetic research analog or fragment used so laboratories can work with a defined sequence without isolating the native protein. Published literature on thymosin β4 covers cytoskeletal dynamics, cell migration, and experimental wound models. Vybe lists this reagent for in-vitro and laboratory study only.

Research areas

Framed as published laboratory and clinical literature. Not treatment guidance.

Actin sequestration and cell motility

Thymosin β4 binds monomeric G-actin and participates in cytoskeletal remodeling. Cell-culture papers use it to probe migration, spreading, and polarity.

Experimental injury models

Animal studies have examined dermal, corneal, and cardiac injury after thymosin β4 exposure, reporting changes in inflammation markers and matrix remodeling. These are research observations, not care instructions.

Published research

Thymosin beta 4 and angiogenesis: modes of action
Vitamins and Hormones · 2016
PMID 27125747 · DOI 10.1016/bs.vh.2016.04.002
Open source
Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications
Expert Opinion on Biological Therapy · 2012
PMID 22074294 · DOI 10.1517/14712598.2012.634793
Open source

Storage & handling

Store lyophilized vials desiccated and protected from light, as stated on the certificate of analysis. Do not interpret storage notes as a protocol for preparing injections or personal use.

Frequently asked questions

What is TB-500?

A research catalog name for synthetic material related to thymosin β4, an actin-binding peptide. Sold only as a laboratory reagent.

What is its CAS number?

Thymosin β4 is commonly indexed as CAS 77591-33-4. Confirm the lot certificate for the exact sequence supplied.

Is this sold for human use?

No. Laboratory research use only. Not for human or veterinary use.

Key facts

Full name: Thymosin beta-4 (TB-500 refers to a synthetic fragment used in research catalogs)
Common name: TB-500
CAS number: 77591-33-4
Molecular formula: C212H350N56O78S
Molecular weight: 4963.49
Research category: Tissue Repair
Storage: Store lyophilized vials desiccated and protected from light, as stated on the certificate of analysis. Do not interpret storage notes as a protocol for preparing injections or personal use.