What is MOTS-c?
A 16-residue mitochondrial-derived peptide used in AMPK and metabolic-flexibility laboratory models.
Research use only. Not for human or veterinary use.
MOTS-c
Reference profile — not currently in the Vybe catalog
Overview
MOTS-c is encoded by a short open reading frame in mitochondrial 12S rRNA. Preclinical papers describe AMPK-related signaling, insulin-sensitivity measures, and exercise-mimetic endpoints in rodents. Vybe lists the synthetic peptide as a research reagent. Nothing here is an exercise or metabolic treatment plan.
Research areas
Framed as published laboratory and clinical literature. Not treatment guidance.
AMPK and nutrient-sensing assays
Cell and animal studies report AMPK activation and changes in glucose disposal after experimental MOTS-c exposure.
Published research
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Cell Metabolism · 2015
PMID 25738455 · PMCID PMC4350667 · DOI 10.1016/j.cmet.2015.02.009
Open source
Storage & handling
Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.
Frequently asked questions
What is MOTS-c?
MOTS-c is documented in the laboratory literature summarized on this page. Vybe lists it as a research reagent only.
What is its CAS number?
1627580-64-6
Is this sold for human use?
No. Laboratory research use only. Not for human or veterinary use.
Where can I view published research?
The PubMed, PMC, and DOI links on this page open the original papers. Vybe is not the scientific publisher.
Key facts
- Full name
- MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c)
- Common name
- MOTS-c
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.55
- Research category
- Metabolic
- Storage
- Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.