What is Melanotan II?

A cyclic α-MSH analog used in melanocortin-receptor pharmacology, including MC1R, MC3R, and MC4R assays.

Research use only. Not for human or veterinary use.

MelanotanII

Reference profile — not currently in the Vybe catalog

Overview

Melanotan II is a lactam-bridged heptapeptide analog of α-MSH. Published receptor profiles are broader than Melanotan I. It is not an approved tanning product. Vybe supplies it only as a documented research peptide; pigmentation anecdotes are not part of this page.

Research areas

Framed as published laboratory and clinical literature. Not treatment guidance.

Multi-subtype melanocortin assays

Binding and cAMP papers compare MT-II across MC1, MC3, MC4, and MC5 receptors in transfected cells and tissues.

Published research

Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics
Journal of Medicinal Chemistry · 1989
PMID 2550623 · DOI 10.1021/jm00131a003
Open source

Storage & handling

Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.

Frequently asked questions

What is Melanotan II?

Melanotan II is documented in the laboratory literature summarized on this page. Vybe lists it as a research reagent only.

What is its CAS number?

121062-08-6

Is this sold for human use?

No. Laboratory research use only. Not for human or veterinary use.

Where can I view published research?

The PubMed, PMC, and DOI links on this page open the original papers. Vybe is not the scientific publisher.

Key facts

Full name: Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2)
Common name: Melanotan II
CAS number: 121062-08-6
Molecular formula: C50H69N15O9
Molecular weight: 1024.18
Research category: Sun Protection
Storage: Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.