What is Melanotan I?

A linear α-MSH analog studied for melanocortin-1 receptor activity and photoprotection research.

Research use only. Not for human or veterinary use.

Melanotan I

Reference profile — not currently in the Vybe catalog

Overview

Melanotan I is the research name for afamelanotide ([Nle4, D-Phe7]-α-MSH). Receptor papers and photobiology studies examine MC1R-driven eumelanin synthesis. A licensed implant exists for specific photosensitivity indications; that medical product is not this catalog listing. Research vials are laboratory reagents only.

Research areas

Framed as published laboratory and clinical literature. Not treatment guidance.

MC1R and pigmentation assays

In-vitro melanocyte and binding studies map potency at melanocortin-1 receptors and downstream melanogenesis markers.

Published research

Afamelanotide for Erythropoietic Protoporphyria
New England Journal of Medicine · 2015
PMID 26132941 · PMCID PMC4780265 · DOI 10.1056/NEJMoa1411481
Open source

Storage & handling

Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.

Frequently asked questions

What is Melanotan I (afamelanotide)?

Melanotan I (afamelanotide) is documented in the laboratory literature summarized on this page. Vybe lists it as a research reagent only.

What is its CAS number?

75921-69-6

Is this sold for human use?

No. Laboratory research use only. Not for human or veterinary use.

Where can I view published research?

The PubMed, PMC, and DOI links on this page open the original papers. Vybe is not the scientific publisher.

Key facts

Full name: Afamelanotide (NDP-MSH, Melanotan I)
Common name: Melanotan I
CAS number: 75921-69-6
Molecular formula: C78H111N21O19
Molecular weight: 1646.85
Research category: Sun Protection
Storage: Keep lyophilized material sealed, desiccated, and protected from light as stated on the lot certificate. This is laboratory storage guidance only — not a reconstitution or administration protocol.