What is CJC-1295 / Ipamorelin?

A two-component research blend pairing a GHRH-receptor analog with a ghrelin-receptor hexapeptide, used in pituitary-axis laboratory work.

Research use only. Not for human or veterinary use.

CJC-1295 /Ipamorelin

Reference profile — not currently in the Vybe catalog

Overview

CJC-1295 generally denotes a tetrasubstituted GRF(1-29) analog; “no DAC” indicates the Drug Affinity Complex moiety is absent, so the sequence is the shorter modified GRF peptide. Ipamorelin is a pentapeptide ghrelin-receptor agonist with published selectivity versus cortisol and prolactin in animal assays. Combined listings let a laboratory hold both ligands in one vial. Each lot’s certificate states the masses present. This is not a dosing pair and is not for human use.

Research areas

Framed as published laboratory and clinical literature. Not treatment guidance.

GHRH receptor ligands

Modified GRF peptides are used to study GHRH-receptor potency, plasma stability, and GH pulse patterns in preclinical models.

Ghrelin-receptor (GHS-R1a) ligands

Ipamorelin papers describe receptor selectivity and GH release in rats and other laboratory species without the same ACTH/cortisol signature reported for some older secretagogues.

Published research

Ipamorelin, the first selective growth hormone secretagogue
European Journal of Endocrinology · 1998
PMID 9849822 · DOI 10.1530/eje.0.1390552
Open source
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone
Journal of Clinical Endocrinology & Metabolism · 2006
PMID 16352683 · DOI 10.1210/jc.2005-1536
Open source

Storage & handling

Store the lyophilized blend as directed on the lot certificate. Protect from moisture and light. No administration protocol is supplied.

Frequently asked questions

What is this blend?

A laboratory pairing of a modified GRF analog (CJC-1295 without DAC) and ipamorelin. Identity and quantity of each component are on the certificate of analysis.

Is this sold for human use?

No. Research reagents only. Not for human or veterinary use.

Key facts

Full name: CJC-1295 (modified GRF 1-29) with ipamorelin (selective ghrelin-receptor agonist)
Common name: CJC-1295 / Ipamorelin
CAS number: 863288-34-0
Molecular formula: Blend — see individual sequences on the lot certificate
Molecular weight: Blend — confirm each component on the COA
Research category: Longevity
Storage: Store the lyophilized blend as directed on the lot certificate. Protect from moisture and light. No administration protocol is supplied.