What is 5-Amino-1MQ?
A small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor employed in adipocyte and NAD-metabolism research.
Research use only. Not for human or veterinary use.
5-Amino-1MQ
Reference profile — not currently in the Vybe catalog
Overview
5-Amino-1-methylquinolinium is used in papers that knock down or inhibit NNMT to study methyl-donor pools and adipocyte metabolism. It is a chemical reagent, not a peptide, and is listed when the catalog includes that research tool. Handle according to the laboratory’s chemical-hygiene plan and the lot paperwork.
Research areas
Framed as published laboratory and clinical literature. Not treatment guidance.
NNMT inhibition
Cell-culture studies use 5-amino-1MQ to reduce NNMT activity and observe changes in SAM/NAD-related metabolites.
Published research
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
Nature Medicine · 2014
PMID 24759208 · PMCID PMC4096716 · DOI 10.1038/nm.3481
Open source
Storage & handling
Store as a dry solid per the certificate, away from moisture and light. Consult the SDS for laboratory handling. Not a consumer product.
Frequently asked questions
What is 5-Amino-1MQ?
A research inhibitor of nicotinamide N-methyltransferase used in metabolic cell models.
Is this sold for human use?
No. Chemical research reagent only.
Key facts
- Full name
- 5-Amino-1-methylquinolinium (NNMT inhibitor used in metabolic cell models)
- Common name
- 5-Amino-1MQ
- CAS number
- 42464-96-0
- Molecular formula
- C10H11N2
- Molecular weight
- 159.21
- Research category
- Metabolic
- Storage
- Store as a dry solid per the certificate, away from moisture and light. Consult the SDS for laboratory handling. Not a consumer product.